StatQuest: A gentle introduction to ChIP-Seq

  • 🎬 Video
  • ℹ️ Published 5 years ago

ChIP-seq, like RNA-seq, sounds mysterious and complicated, but it's not. Here's a gentle introduction to the subject that covers the basics behind the experiment, how the data is processed and the sorts of things you can do with it.

It's based on the original RNA-seq StatQuest, so make sure you watch that first (or at least are all ready totally down with that material):

For a complete index of all the StatQuest videos, check out:

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💬 Comments

It is amazingly well-produced and explained in detailed. I can see a logical order which makes perfect sense. I would like to see other methods, like ATAC-seq, DAP-seq, STAR-seq, etc. Please keep doing more!

Author — Dawgs Athens


Best explanation. After reading so many literature also, I am unable to understand fully. You explained in just 8 minute. Great job.

Author — ankit agrawal


Hi Josh, can you do a statquest on ATAC-seq? Thank you very much!

Author — Muhammet Memon


Very beautiful and simple explanation. Thank you so much for that! It is going to help me a lot for my human genomics exam :)

Author — Brkhr a.k.a. Legatus31


Wow. Josh, thank you for an incredibly helpful video.
As a first year Ph.D student this eased/clarified concepts/procedures that I missed in the ChIP class.


Author — David Tovar


It's amazing how well you explain this, and not only this (I've seen other vids of yours). I'm a telecom engineer in process of turning into a would-be data scientist and I've understood it! BAM!! ;)

Author — Gerardo de Miguel


Really living for the enthusiasm, Josh. Love the intro/outro.

Author — Mari Amirbekyan


thanks for making this simple and gentle, very effective!

Author — Fiona


Hi Josh, your videos are awesome! Could you consider doing one on ATAC-seq??

Author — Seth Fortmann


I feel like you explained this to us like we are five year olds which was really helpful. Thank you so much!

Author — mr.beancouldbreakmyspleen


Great video! I linked your video in my Medium article on predicting transcription factor-DNA binding using deep learning, and also my video (coming soon!) on the same topic in the description box. Thanks for the awesome explanation!

Author — Gracelyn Shi


Best explanation ever...Loved it! Thank you so much for this.

Author — Bhagyashree Hote


Excellent and organized presentation. Thank you!

Author — Habeeb S K M


Thank you so much for making this so straightforward and easy to understand!!! It's so easy to find way too much info online that has loads of crap added in, but this allowed me to understand it nicely! Keep it up :D

Author — Alex Leung


Found this channel and instantly subscribed. The whole style of your explanations is great! Keep up the great work :)

Author — misterchees


Extremely comprehensive and lucid! Thanks!!!

Author — Chandrama Ghosh


This is incredibly well explained. Thank you!

Author — Omair Shariq


Thanks so much for the explanation, it was really helpful!!

Author — Dario Dedja


Hi Josh, I find your videos very helpful! thank you so much! I realized the the index doesn't contain this video. Would you mind updating the index some time?

Author — Jiaoyang Dong


Great video, as always :)! Helps me a lot how to phrase what am I doing.. but regarding the control, what would you like to recommend, GFP or total input in case of plants?

Author — Emese Dr. Szabó